Lise Létourneau was born in the heart of the Boreal forest in L'Annonciation, Quebec, in the Upper Laurentians. After finishing her studies at the School of Fine Arts and the University of Quebec in Montreal, she returned to her hometown in 1972 and worked as an art therapist.
It wasn't until 1990 that she launched her artistic career. In 1995, a grant from the Arts Council of Quebec enabled her to present her first solo show, Du rituel à la mémoire (From Ritual to Memory) at the Glendon Gallery of York University in Toronto. Between 1996 and 1999, another major show, Témoins muets (Silent witnesses), toured well-known exhibition centers in Quebec. In 1998, she participated in the symposium Proximité in Victoriaville, Quebec, and in 2001, in the event known as La piste de l'art (The Art Trail), organized by Praxis Art Actuel.
Since 1993 she has participated in a number of group shows in Quebec, Canada and Europe.
Lise Létourneau is a member of the Quebec Council of Textile Art, Praxis Art Actuel, and of the multidisciplinary group The Precambrians.